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Showing 1 to 12 of 100 entries
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Equine Influenza.

Cold Spring Harbor perspectives in medicine

Chambers TM.
PMID: 32152243
Cold Spring Harb Perspect Med. 2020 Mar 09; doi: 10.1101/cshperspect.a038331. Epub 2020 Mar 09.

Horses are the third major mammalian species, along with humans and swine, long known to be subject to acute upper respiratory disease from influenza A virus infection. The viruses responsible are subtype H7N7, which is believed extinct, and H3N8,...

Erratum: Bone Tropism in Cancer Metastases.

Cold Spring Harbor perspectives in medicine

Wang H, Zhang W, Bado I, Zhang XH.
PMID: 31676496
Cold Spring Harb Perspect Med. 2019 Nov 01;9(11). doi: 10.1101/cshperspect.a039016.

No abstract available.

Neonatal Opioid Withdrawal Syndrome (NOWS): A Transgenerational Echo of the Opioid Crisis.

Cold Spring Harbor perspectives in medicine

Weller AE, Crist RC, Reiner BC, Doyle GA, Berrettini WH.
PMID: 32229609
Cold Spring Harb Perspect Med. 2021 Mar 01;11(3). doi: 10.1101/cshperspect.a039669.

The incidence of neonatal opioid withdrawal syndrome (NOWS) has increased substantially in the setting of the opioid epidemic, a major public health problem in the United States. At present, NOWS has commonly used assessment and treatment protocols, but new...

H7N9 Influenza Virus in China.

Cold Spring Harbor perspectives in medicine

Li C, Chen H.
PMID: 32205415
Cold Spring Harb Perspect Med. 2021 Aug 02;11(8). doi: 10.1101/cshperspect.a038349.

In early 2013, human infections caused by a novel H7N9 avian influenza virus (AIV) were first reported in China; these infections caused severe disease and death. The virus was initially low pathogenic to poultry, enabling it to spread widely...

Neural Substrates and Circuits of Drug Addiction.

Cold Spring Harbor perspectives in medicine

Feltenstein MW, See RE, Fuchs RA.
PMID: 32205414
Cold Spring Harb Perspect Med. 2021 Apr 01;11(4). doi: 10.1101/cshperspect.a039628.

Drug addiction is a chronic relapsing disorder, and a significant amount of research has been devoted to understand the factors that contribute to the development, loss of control, and persistence of compulsive addictive behaviors. In this review, we provide...

A History of Cancer Research: Carcinogens and Mutagens.

Cold Spring Harbor perspectives in medicine

Lipsick J.
PMID: 33649023
Cold Spring Harb Perspect Med. 2021 Mar 01;11(3). doi: 10.1101/cshperspect.a035857.

Observations of the incidence of tumors among chimney sweeps in the eighteenth century and later experiments with coal tars provided early evidence that carcinogens in the environment can promote cancer. Subsequent studies of individuals exposed to radiation, work on...

Mendelian Randomization.

Cold Spring Harbor perspectives in medicine

Birney E.
PMID: 34872952
Cold Spring Harb Perspect Med. 2021 Dec 06; doi: 10.1101/cshperspect.a041302. Epub 2021 Dec 06.

Mendelian randomization borrows statistical techniques from economics to allow researchers to analyze the effects of the environment, drug treatments, and other factors on human biology and disease. Taking advantage of the fact that genetic variation is randomized among children...

The Epidemiology, Virology, and Pathogenicity of Human Infections with Avian Influenza Viruses.

Cold Spring Harbor perspectives in medicine

Wang D, Zhu W, Yang L, Shu Y.
PMID: 31964651
Cold Spring Harb Perspect Med. 2021 Apr 01;11(4). doi: 10.1101/cshperspect.a038620.

Influenza is a global challenge, and future pandemics of influenza are inevitable. One of the lessons learned from past pandemics is that all pandemic influenza viruses characterized to date possess viral genes originating from avian influenza viruses (AIVs). During...

Opioid Modulation of the Gut-Brain Axis in Opioid-Associated Comorbidities.

Cold Spring Harbor perspectives in medicine

Zhang L, Roy S.
PMID: 32816876
Cold Spring Harb Perspect Med. 2021 Sep 01;11(9). doi: 10.1101/cshperspect.a040485.

Growing evidence from animal and human studies show that opioids have a major impact on the composition and function of gut microbiota. This leads to disruption in gut permeability and altered microbial metabolites, driving both systemic and neuroinflammation, which...

Animal Models of the Behavioral Symptoms of Substance Use Disorders.

Cold Spring Harbor perspectives in medicine

Vanderschuren LJMJ, Ahmed SH.
PMID: 32513674
Cold Spring Harb Perspect Med. 2021 Aug 02;11(8). doi: 10.1101/cshperspect.a040287.

To more effectively manage substance use disorders, it is imperative to understand the neural, genetic, and psychological underpinnings of addictive behavior. To contribute to this understanding, considerable efforts have been made to develop translational animal models that capture key...

Innate Immunity in Hepatitis C Virus Infection.

Cold Spring Harbor perspectives in medicine

Schwerk J, Negash A, Savan R, Gale M.
PMID: 32341066
Cold Spring Harb Perspect Med. 2021 Feb 01;11(2). doi: 10.1101/cshperspect.a036988.

Activation and viral control of the innate immune response are hallmarks of hepatitis C virus (HCV) infection and are major determinants of spontaneous clearance or progression to chronic infection and liver disease. In this review, we provide a contemporary...

Emerging HxNy Influenza A Viruses.

Cold Spring Harbor perspectives in medicine

Liu WJ, Wu Y, Bi Y, Shi W, Wang D, Shi Y, Gao GF.
PMID: 32928891
Cold Spring Harb Perspect Med. 2020 Sep 14; doi: 10.1101/cshperspect.a038406. Epub 2020 Sep 14.

The continuous emergence and reemergence of diverse subtypes of influenza A viruses, which are known as "HxNy" and are mediated through the reassortment of viral genomes, account for seasonal epidemics, occasional pandemics, and zoonotic outbreaks. We summarize and discuss...

Showing 1 to 12 of 100 entries